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C53-04 Cocaine Cuts Deep: A Rare Case of Levamisole-Induced Thrombotic Vasculitis in a Critically Ill Patient

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To present a rare case of levamisole-induced thrombotic vasculitis in a critically ill patient and its implications in management.
A case report of a 33-year-old man with end-stage renal disease and cocaine use presenting with severe symptoms and laboratory findings.
Diagnostic imaging and lab work including blood cultures, echocardiography, and biopsy were conducted to assess causative factors.
Multidisciplinary consultations aided in the management of symptoms and complications.
Confirmed diagnosis of levamisole-induced thrombotic vasculitis following biopsy findings.
Patient experienced progressive necrotic plaques despite treatment, necessitating ongoing multidisciplinary care.
Management challenges included balancing infection control and prevention of immune suppression.

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Case reports levamisole-induced thrombotic vasculitis in patient with end-stage renal disease, emphasizing diagnostic challenges.

Lugo et al. (2026) studied this question.

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