Why the study?
Is left ventricular longitudinal systolic function, as measured by 2D speckle-tracking echocardiography, significantly altered in patients with HFpEF compared to controls?
Population
2,284 patients with heart failure with preserved ejection fraction (HFpEF) and 2,302 controls
Comparison
2D speckle-tracking echocardiography vs Controls
Design
Meta-analysis
Authors
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May refine HFpEF risk stratification via GLS; leaves open therapeutic implications.
Is left ventricular longitudinal systolic function, as measured by 2D speckle-tracking echocardiography, significantly altered in patients with HFpEF compared to controls?
This meta-analysis confirms that left ventricular longitudinal systolic function is significantly impaired in patients with HFpEF, highlighting the potential prognostic role of abnormal global longitudinal strain.
Morris et al. (2017) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: