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April 4, 2026Journal of university of Anbar for pure scienceOpen Access

Bacteriophage therapy as an alternative approach: The future of phage-based treatments in combating antibiotic resistance

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Authors

RSRiyam SalihSMSaad Mutlk.

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Overview

Investigation reveals phage-based treatment effectiveness in burn wound infections amidst antibiotic resistance.

Key Points

  • This research aims to explore bacteriophage therapy as a potential treatment for drug-resistant infections in burn wounds.
  • Collected 100 burn wound swabs from patients in Ramadi City.
  • Identified bacterial isolates through culture, microscopy, and biochemical testing.
  • Assessed antimicrobial susceptibility using the Kirby-Bauer disk diffusion method.
  • Isolated bacteriophages from wastewater using the double agar layer method and characterized them via TEM.
  • Isolated 86 bacterial strains, with Staphylococcus aureus being the most predominant (54%).
  • Lytic bacteriophages were effective against S. aureus but not against E. coli, P. aeruginosa, or K. pneumoniae.
  • Bacteriophages exhibited strong host specificity towards S. aureus, implying potential for targeted therapy.

Cite This Study

Salih et al. (2026) studied this question.

synapsesocial.com/papers/69d0aefd659487ece0fa4d91https://doi.org/10.37652/juaps.2025.162200.1479
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Topical Polyethylene Glycol-Phage Ointment as a Therapy to Treat Burn-Wound Infection Using Mice Model2024 · 1 citations
  2. 2Bacteriophage therapy reduces <i>Staphylococcus aureus</i> in a porcine and human <i>ex vivo</i> burn wound infection model2024 · 15 citations
  3. 3Isolation and characterization of bacteriophages from sewerage water targeting methicillin resistance S. aureus in burn patients2024
  4. 4Phage therapy for burn wound infections in the era of antibiotic resistance2024 · 1 citations
  5. 5Evaluating Indigenous Lytic Bacteriophages for Activity Against Multi-Resistant Enterobacteriaceae2026