This research demonstrates regioselective addition of N-hydroxyl imides to internal alkynes, suggesting new pathways for chemical transformation.
An intermolecular rhodium‐catalyzed regioselective addition of N ‐hydroxyl imides to internal alkynes leads to branched O ‐allyl compounds, which can be readily transformed to allylic alcohols and O ‐allyl hydroxylamines after deprotection. Isotopic labeling experiments suggest a plausible reaction mechanism.
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Liu et al. (2026) studied this question.
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