Synthetic methodology demonstrates efficient rhodium-catalyzed N-allylation of sulfoximines using alkyl alkynes, indicating a mild route to diverse branched allylic derivatives.
Rhodium-catalyzed N-allylation coupling reactions of sulfoximines with alkyl alkynes have been reported. The branched allylic products were obtained with a rhodium catalyst under mild reaction conditions and provided good to excellent yields of N-allylic sulfoximines. This protocol provides efficient access to diverse N-allylic sulfoximine derivatives, showing broad functional group compatibility and substantial substrate scope.
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Chen et al. (2026) studied this question.
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