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This review explores the efficacy of green-synthesised gold nanoparticles for targeted cancer treatment, indicating a sustainable approach to biomedical innovation.
This review article focuses on the biological synthesis, characterisations and mechanism of action of gold nanoparticles (AuNPs) as an anticancer agent. The article explores various aspects, such as reactive oxygen species, cytotoxicity, and targeted delivery. Several research reports illustrate that green-synthesised AuNPs act as a reducing and stabilising agent. Biosynthesised AuNPs were characterised by various techniques like UV–Vis spectroscopy, SEM, TEM, and FTIR to determine attributes of nanoparticles. Cytotoxicity and anticancer activity were evaluated against cancer cell lines. This article summarises several research reports where AuNPs showed lower toxicity towards normal cell lines than cancer cells via ROS, disruption in physiological and metabolic processes, and apoptosis. AuNPs provide a versatile and efficient approach for cancer due to their ability to target specific sites and biocompatibility. Nanotechnology, by using green synthesis of AuNPs, holds promise for creating advanced and personalised treatment against cancer in the future.
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Saini et al. (2026) studied this question.
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