Cefazolin inoculum effect and cefazolin microbiological treatment failure in serious methicillin-susceptible Staphylococcus aureus infections: A multi-center retrospective cohort study
The study aims to evaluate the relationship between cefazolin inoculum effect and treatment failure in serious MSSA infections.
Conducted a multi-center retrospective cohort analysis
Analyzed patient data with serious MSSA infections
Evaluated the impact of cefazolin inoculum effect on treatment outcomes.
Cefazolin inoculum effect significantly increased risk of microbiological treatment failure
CzIE testing may provide guidance for antibiotic treatments.
Resumen
CzIE was associated with a significantly increased risk of microbiological treatment failure. CzIE testing may be useful in guiding antibiotic treatment for serious MSSA infections.