Does non-insulin-dependent diabetes mellitus independently affect cardiac structure and function?
Non-insulin-dependent diabetes mellitus independently causes adverse changes in cardiac structure and function, which may contribute to increased cardiovascular events.
Non-insulin-dependent DM has independent adverse cardiac effects, including increased LV mass and wall thicknesses, reduced LV systolic chamber and myocardial function, and increased arterial stiffness. These findings identify adverse cardiovascular effects of DM, independent of associated increases in BMI and arterial pressure, that may contribute to cardiovascular events in diabetic individuals.
Devereux et al. (Tue,) studied this question.