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December 8, 2020BMJOpen Access

Association between low density lipoprotein and all cause and cause specific mortality in Denmark: prospective cohort study

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Authors

CJCamilla Ditlev Lindhardt JohannesenALAnne LangstedMMMartin Bødtker Mortensen

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Overview

Prospective cohort study reveals a U-shaped association between LDL cholesterol and all-cause mortality in the general population, suggesting lowest risk occurs at moderate concentrations.

Key Points

  • To assess the relationship between low-density lipoprotein cholesterol concentrations and the risk of all-cause and cause-specific mortality in the general population.
  • Prospective cohort study conducted in Denmark evaluating individuals from the general population.
  • Both low and high levels of LDL-C were associated with an increased risk of all-cause mortality.
  • The lowest risk of all-cause mortality was observed at an LDL-C concentration of 3.6 mmol/L (140 mg/dL).

Cite This Study

Johannesen et al. (2020) studied this question.

synapsesocial.com/papers/69d457f669b4577cb48c8a3ahttps://doi.org/10.1136/bmj.m4266
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