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April 7, 2026Pediatric Dermatology

Shining Light on Treatments: A Systematic Review of Existing Therapies for Pediatric Segmental Vitiligo

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Authors

HGHira GhaniVHV.M. HoffmanASAsghar Shah

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Overview

This systematic review assesses treatment effectiveness for pediatric segmental vitiligo, highlighting important findings.

Key Points

  • To evaluate the safety and efficacy of existing and emerging treatments for pediatric segmental vitiligo.
  • Conducted a systematic literature search in multiple databases from March to April 2025
  • Included randomized controlled trials, case reports, case series, and cohort studies
  • Focused on studies published in the last 10 years regarding pediatric segmental vitiligo treatments
  • 10 studies involving 2085 pediatric patients (843 with segmental vitiligo) were included
  • Repigmentation rates varied, with some studies reporting over 70% in facial lesions
  • Adverse events were mild, primarily consisting of burning and erythema
  • Moderate-to-low quality of evidence and moderate risk of bias observed

Cite This Study

Ghani et al. (2026) studied this question.

synapsesocial.com/papers/69d49fe5b33cc4c35a2285cdhttps://doi.org/10.1111/pde.70215
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