Why the study?
Does a standardized pulmonary vein isolation workflow aiming for contiguous lesions improve 12-month freedom from arrhythmias in patients with paroxysmal atrial fibrillation?
Does a standardized pulmonary vein isolation workflow aiming for contiguous lesions improve 12-month freedom from arrhythmias in patients with paroxysmal atrial fibrillation?
A standardized pulmonary vein isolation workflow aiming for contiguous lesions achieves high acute success and approximately 80% freedom from arrhythmias at 12 months in patients with paroxysmal atrial fibrillation.
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Supports standardized contiguous-lesion PVI workflows in paroxysmal AF; hypothesis-generating and requires randomized confirmation before practice change.
The VISTAX trial demonstrated that a standardized PAF ablation workflow aiming for contiguous lesions leads to low rates of PAEs, high acute first-pass isolation rates, and 12-month freedom from arrhythmias approaching 80%. Further research is needed to improve the reproducibility of the outcomes across a wider range of centres.Clinical trial registration: ClinicalTrials.gov, number NCT03062046, https://clinicaltrials.gov/ct2/show/NCT03062046.
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Duytschaever et al. (2020) studied this question.
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