Why the study?
Which QT correction formula is preferred for the assessment of drug-induced QT interval prolongation?
Which QT correction formula is preferred for the assessment of drug-induced QT interval prolongation?
The Hodges formula and Nomogram method are preferred over Bazett's formula for assessing drug-induced QT prolongation, especially at heart rates deviating from 60 bpm.
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Avoid Bazett's for DeltaQTc assessment away from 60 bpm; leaves optimal formula choice open pending higher-level validation.
Chiladakis et al. (2010) studied this question.
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