Why the study?
Does myocardial constructive work predict left ventricular fibrosis in patients with hypertrophic cardiomyopathy?
Does myocardial constructive work predict left ventricular fibrosis in patients with hypertrophic cardiomyopathy?
Myocardial constructive work is impaired in hypertrophic cardiomyopathy even when LVEF is normal, and it serves as a predictor for left ventricular fibrosis.
May flag subclinical fibrosis in HCM with preserved LVEF; hypothesis-generating and requires prospective validation before clinical use.
Global constructive work is significantly reduced in HCM despite normal LVEF and is associated with the LV fibrosis as assessed by LGE.
No takes yet. Share an insight, caveat, or question.
Galli et al. (2018) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: