In patients with hypertrophic cardiomyopathy, left atrial remodeling and dysfunction are driven primarily by LV mass index rather than myocardial fibrosis.
LV mass index may predominate over fibrosis in HCM-related LA remodeling; hypothesis-generating and requires prospective validation.
HCM patients showed progressed LA remodeling and dysfunction; the determinant of LA remodeling and dysfunction was LV mass index rather than LV myocardial fibrosis by LGE-magnetic resonance imaging.
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Kim et al. (2016) studied this question.
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