Why the study?
The physiological effect of adenosine in the infarct-related artery during STEMI intervention is variable, and coronary steal facilitated by collaterals can occur.
Does adenosine administration induce coronary steal in patients presenting with ST-segment-elevation myocardial infarction?
Population
93 patients presenting with STEMI undergoing pressure-wire assessment after PCI
Comparison
Coronary steal (CFR <0.9) vs no change (CFR=0.9-1.1) vs hyperemic flow (CFR >1.1) after adenosine
Design
Physiological cohort study
Authors
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Coronary steal may underlie inconsistent adenosine responses in STEMI no-reflow; leaves open optimal patient selection for future trials.
Does adenosine administration induce coronary steal in patients presenting with ST-segment-elevation myocardial infarction?
Adenosine-induced coronary steal occurs in a proportion of STEMI patients and is associated with higher collateral flow and microvascular resistance, potentially explaining variable responses to adenosine in treating no-reflow.
Aetesam‐ur‐Rahman et al. (2021) studied this question.
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