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August 14, 2007Circulation713 citationsOpen Access

Prognostic Value of Very Low Plasma Concentrations of Troponin T in Patients With Stable Chronic Heart Failure

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RLRoberto LatiniSMSerge MassonIAInder S. Anand

Structured PICO

Does detectable cTnT at very low plasma concentrations predict adverse outcomes in patients with stable chronic heart failure?

P
Population
Patients with stable chronic heart failure
I
Intervention
Measurement of cardiac troponin T (cTnT) using a highly sensitive assay
O
Outcome
Adverse outcomes

Highly sensitive troponin T assays can detect very low concentrations of cTnT that retain prognostic value for adverse outcomes in stable chronic heart failure.

Abstract

In this large population of patients with HF, detectable cTnT predicts adverse outcomes in chronic HF. By the highly sensitive assay, troponin T retains a prognostic value at previously undetectable concentrations.

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Cite This Study

Latini et al. (2007) studied this question.

synapsesocial.com/papers/69d56c2075589c71d767cbedhttps://doi.org/10.1161/circulationaha.106.655076
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cardiac-Specific Troponin I Levels to Predict the Risk of Mortality in Patients with Acute Coronary Syndromes1996 · 1,776 citations
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  3. 3Myocardial infarction redefined—a consensus document of The Joint European Society of Cardiology/American College of Cardiology committee for the redefinition of myocardial infarction2000 · 4,854 citations
  4. 4Prognostic Value of Combination of Cardiac Troponin T and B-Type Natriuretic Peptide after Initiation of Treatment in Patients with Chronic Heart Failure2003 · 95 citations
  5. 5Time‐Dependent ROC Curves for Censored Survival Data and a Diagnostic Marker2000 · 2,965 citations