Key result
High-sensitive troponin T was significantly elevated in chronic heart failure patients compared to healthy controls (0.018 vs 0.003 ng/mL, p<0.001) and predicted mortality and rehospitalization.
Why the study?
Does high-sensitive troponin T correlate with disease severity and provide independent prognostic information in patients with chronic heart failure?
Case-Control (n=233)
Does high-sensitive troponin T correlate with disease severity and provide independent prognostic information in patients with chronic heart failure?
Absolute Event Rate: 0.018% vs 0.003%
p-value: p=<0.001
High-sensitive troponin T is elevated in chronic heart failure, correlates with disease severity, and provides prognostic information independent of and additive to NT-proBNP.
No takes yet. Share an insight, caveat, or question.
May refine prognostication in chronic HF beyond NT-proBNP; hypothesis-generating and requires prospective validation.
Jungbauer et al. (2011) conducted a case-control in Chronic heart failure (n=233). High-sensitive troponin T (hs-cTnT) vs. Healthy controls was evaluated on hs-cTnT levels (p=<0.001). High-sensitive troponin T was significantly elevated in chronic heart failure patients compared to healthy controls (0.018 vs 0.003 ng/mL, p<0.001) and predicted mortality and rehospitalization.
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