Why the study?
High-sensitivity cardiac troponin T is a detectable prognostic biomarker in heart failure, but its prognostic role over time in ischemic versus non-ischemic heart failure required evaluation.
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Comparison
IHF vs NIHF groups
Follow-up
1 year
Serial hs-cTnT may refine HF risk stratification; leaves open differential prognostic value in IHF versus NIHF.
INTRODUCTION: High-sensitivity cardiac troponin T (hs-cTnT) as a prognostic biomarker can be detected in patients with heart failure (HF). AIM: This study focuses on hs-cTnT to evaluate its prognostic role in ischemic heart failure (IHF) and non-ischemic heart failure (NIHF). MATERIAL AND METHODS: One hundred and sixty patients with HF were divided into IHF and NIHF groups. Hs-cTnT measured at baseline, 2-5 h, 6-24 h and 24 h-7 d after admission was analyzed by generalized estimating equations. Patients were followed up for 1 year at the endpoint events of re-hospitalization for HF and all-cause death that was tested by the Kaplan-Meier method and the Cox regression method. RESULTS: < 0.05). CONCLUSIONS: Hs-cTnT varying over time is an important risk factor for the prognosis of patients with IHF and NIHF.
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Li et al. (2021) studied this question.
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