April 17, 2017Circulation
High-Sensitive Cardiac Troponin for Prediction of Clinical Heart Failure
Key result
Participants with the highest troponin T concentrations had a 5- and 6-fold increase in the incidence of death and heart failure, respectively, compared with those with undetectable levels.
Design
Editorial
Authors
Discussion
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Implication
High-sensitivity cardiac troponin is a promising biomarker for identifying individuals at high risk for developing clinical heart failure, complementing other biomarkers like NT-proBNP.
PICO
P
Population
4,221 participants in the Cardiovascular Health Study evaluated for the association between troponin T concentrations and the incidence of death and heart failure.
E
Exposure / Comparator
High troponin T (TnT) concentrations vs Undetectable cTnT levels
O
Primary Outcome
Incidence of death and heart failure — 5- and 6-fold increase
Main Result
Effect estimate: 5- and 6-fold increase
High-sensitivity cardiac troponin is a promising biomarker for identifying individuals at high risk for developing clinical heart failure, complementing other biomarkers like NT-proBNP.
Cite This Study
Gori et al. (2017) conducted an editorial in Heart failure (n=4,221). High troponin T (TnT) concentrations vs. Undetectable cTnT levels was evaluated on Incidence of death and heart failure (5- and 6-fold increase). Participants with the highest troponin T concentrations had a 5- and 6-fold increase in the incidence of death and heart failure, respectively, compared with those with undetectable levels.