Redefining Adverse and Reverse Left Ventricular Remodeling by Cardiovascular Magnetic Resonance Following ST-Segment–Elevation Myocardial Infarction and Their Implications on Long-Term Prognosis
Why the study?
Does adverse LV remodeling at 6 months (defined as ≥12% increase in both LVESV and LVEDV by CMR) predict worse long-term clinical outcomes in stable reperfused STEMI patients?
Population
Stable reperfused patients with ST-segment-elevation myocardial infarction
Comparison
Adverse LV remodeling vs adverse LV remodeling with compensation, reverse LV remodeling, and no LV remodeling
Design
Cohort study
Follow-up
6 months
Authors
Discussion
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Member takes
Implication
Adverse LV remodeling by this CMR definition flags higher-risk post-STEMI patients; hypothesis-generating and requires prospective validation before guiding care.
Structured PICO
Does adverse LV remodeling at 6 months (defined as ≥12% increase in both LVESV and LVEDV by CMR) predict worse long-term clinical outcomes in stable reperfused STEMI patients?
P
Population
Stable reperfused patients with ST-segment-elevation myocardial infarction
I
Intervention
Adverse LV remodeling at 6 months (defined as ≥12% increase in both LVESV and LVEDV by cardiovascular magnetic resonance)
C
Comparator
Adverse LV remodeling with compensation, reverse LV remodeling, and no LV remodeling
O
Outcome
Long-term clinical outcomes
Adverse LV remodeling defined by a ≥12% increase in both LVESV and LVEDV at 6 months post-STEMI identifies patients at higher risk for worse long-term clinical outcomes.
Cite This Study
Bulluck et al. (2020) studied this question.