May 13, 2010ASAIO Journal

A Novel Approach to the In Vitro Hydrodynamic Study of the Aortic Valve: Mock Loop Development and Test

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Population

Untreated porcine aortic root functional unit samples and one ARFU prosthesized with a state-of-the-art…

Comparison

Testing in a novel purposely designed pulsatile… vs Manufacturer data and in vivo postop…

Design

Preclinical

Authors

RVRiccardo VismaraFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico GFGianfranco Beniamino FiorePolitecnico di Milano AMAndrea ManginiUniversity of Milan

Discussion

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Implication

May refine aortic root device testing in vitro; leaves open clinical translation pending human validation studies.

Structured PICO

Population

Untreated porcine aortic root functional unit (ARFU) samples and one ARFU prosthesized with a state-of-the-art bioprosthesis

Intervention

Testing in a novel purposely designed pulsatile mock loop allowing for aortic surgery simulation

Comparator

Manufacturer data and in vivo postop echo-Doppler data

Outcome

Hydrodynamic parameters including valve leakage, effective orifice areas, and pressure dropssurrogate

A novel in vitro mock loop for whole aortic root functional units provides hydrodynamic data that closely mimics in vivo conditions, offering an improved model for aortic surgery simulation.

Cite This Study

Vismara et al. (2010) studied this question.

synapsesocial.com/papers/69d56d3675589c71d767cffc https://doi.org/10.1097/mat.0b013e3181d9c295

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A Novel Approach to the In Vitro Hydrodynamic Study of the Aortic Valve: Mock Loop Development and Test

Discussion

Member takes

Implication

Structured PICO

Cite This Study

A Novel Approach to the In Vitro Hydrodynamic Study of the Aortic Valve: Mock Loop Development and Test

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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Also Consider