April 1, 2001Journal of Clinical Oncology

Congestive Heart Failure After Treatment for Wilms’ Tumor: A Report From the National Wilms’ Tumor Study Group

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Why the study?

Does doxorubicin treatment cause congestive heart failure in children treated for Wilms' tumor?

Population

Children treated for Wilms' tumor

Design

Cohort

Authors

DGDaniel M. GreenPediatric / Congenital Cardiology YGYevgeny GrigorievRoswell Park Comprehensive Cancer Center BNBin NanJiangnan University

Discussion

Member takes

Implication

Supports cardiac monitoring in doxorubicin-treated Wilms tumor survivors; hypothesis-generating for dose reduction to mitigate heart failure risk.

Structured PICO

Does doxorubicin treatment cause congestive heart failure in children treated for Wilms' tumor?

Population

Children treated for Wilms' tumor

Intervention

Doxorubicin

Outcome

Congestive heart failuresafety

Treatment with doxorubicin for Wilms' tumor carries a risk of congestive heart failure in children, highlighting the need to evaluate if dose reduction mitigates this risk.

Cite This Study

Green et al. (2001) studied this question.

synapsesocial.com/papers/69d56dc375589c71d767d045 https://doi.org/10.1200/jco.2001.19.7.1926

Topics

Heart failure HFrEF treatment

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Implication

Supports cardiac monitoring in doxorubicin-treated Wilms tumor survivors; hypothesis-generating for dose reduction to mitigate heart failure risk.

Congestive Heart Failure After Treatment for Wilms’ Tumor: A Report From the National Wilms’ Tumor Study Group

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Congestive Heart Failure After Treatment for Wilms’ Tumor: A Report From the National Wilms’ Tumor Study Group

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

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