What question did this study set out to answer?

To assess hypertension treatment regimens and the rates of blood pressure control among African American adults.

April 1, 2013Journal of Clinical HypertensionOpen Access

Treatment of Hypertension Among African Americans: The Jackson Heart Study

View Full Paper

Ask AI

Bookmark

Why the study?

Does the choice of antihypertensive regimen (such as thiazide diuretics vs calcium channel blockers) improve blood pressure control in treated African American adults?

Key Points

To assess hypertension treatment regimens and the rates of blood pressure control among African American adults.
Evaluated treated hypertensive African American participants in the Jackson Heart Study across examination I (2000–2004, N=2415) and examination II (2005–2008, N=2577).
Measured blood pressure control below 140/90 mm Hg and attainment of the Seventh Report of the Joint National Committee (JNC 7) targets according to medication class and regimen.
Blood pressure was below 140/90 mm Hg in 66% of participants at examination I and 70% at examination II, while JNC 7 targets were reached by 56% and 61%, respectively.
Participants with diabetes or chronic kidney disease, as well as men compared with women, were significantly less likely to achieve target blood pressure.
Thiazide diuretics were the most commonly prescribed agent and correlated with higher control rates, whereas calcium channel blocker monotherapy was significantly less likely to achieve target blood pressure than thiazide monotherapy.

Structured PICO

Does the choice of antihypertensive regimen (such as thiazide diuretics vs calcium channel blockers) improve blood pressure control in treated African American adults?

Population

African American adults with treated hypertension in the Jackson Heart Study (n=2415 at exam I; n=2577 at exam II)

Intervention

Antihypertensive treatment regimens (including thiazide diuretics and calcium channel blockers)

Comparator

Alternative antihypertensive regimens (e.g., non-thiazide users, calcium channel blocker monotherapy compared to thiazide monotherapy)

Outcome

Blood pressure control (BP <140/90 mm Hg and JNC 7 treatment targets)surrogate

In African American adults, thiazide diuretics were associated with better blood pressure control compared to non-thiazide regimens and calcium channel blocker monotherapy.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

May support thiazide preference over CCB monotherapy in African Americans; hypothesis-generating and requires RCTs before practice change.

Cite This Study

Harman et al. (2013) studied this question.

synapsesocial.com/papers/69d56dcb75589c71d767d0ab https://doi.org/10.1111/jch.12088

Topics

Hypertension management

View Full Paper

Ask AI

Bookmark

Implication

May support thiazide preference over CCB monotherapy in African Americans; hypothesis-generating and requires RCTs before practice change.

Treatment of Hypertension Among African Americans: The Jackson Heart Study

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Topics

Treatment of Hypertension Among African Americans: The Jackson Heart Study

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider