Why the study?
Moderate to severe paravalvular-leak regurgitation after surgical aortic-valve replacement or transcatheter valve implantation is associated with heart failure, hemolysis, and poor prognosis, making percutaneous closure an important alternative to surgery.
Authors
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May warrant consideration in selected high-risk APVL patients; leaves open need for prospective trials on outcomes and selection.
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Freixa et al. (2022) studied this question.
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