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May 21, 2015Amyloid180 citations

Atrial fibrillation in amyloidotic cardiomyopathy: prevalence, incidence, risk factors and prognostic role

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SLSimone LonghiCQCandida Cristina QuartaAMAgnese Milandri

Key Points

  • This research aims to explore the prevalence, incidence, risk factors, and outcomes of atrial fibrillation in amyloidotic cardiomyopathy.
  • Data collected on atrial fibrillation prevalence in amyloidotic cardiomyopathy patients.
  • Identified independent risk factors including age, heart failure, left ventricular ejection fraction, and atrial size.
  • Analyzed the relationship between atrial fibrillation and all-cause mortality.
  • Atrial fibrillation prevalence reached 15% on average, rising to 40% in wt-ATTR amyloidosis cases.
  • Independent risk factors for atrial fibrillation included age, heart failure, and left atrial size.
  • Atrial fibrillation correlated strongly with heart failure incidents but did not affect overall mortality.

Abstract

In AC the prevalence of AF varies widely according to etiology with a mean value of 15% that reaches 40% in wt-ATTR amyloidosis. Age, HF, LV ejection fraction, left atrial size and right atrial pressure were the main independent risk factors, while wall thickness and etiology were not the main independent risk factors. AF does not seem to impact all-cause mortality but was strongly associated with prevalent and incident HF.

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Cite This Study

Longhi et al. (2015) studied this question.

synapsesocial.com/papers/69d56e2075589c71d767d404https://doi.org/10.3109/13506129.2015.1028616
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