Why the study?
Much less evidence supports valve-in-ring and valve-in-mitral annulus calcification interventions than valve-in-valve TMVR, with data primarily derived from small case series or voluntary registries.
What is the current evidence for transcatheter mitral valve replacement using transcatheter aortic valves in patients with failing bioprostheses, rings, or severe mitral annulus calcification?
What is the current evidence for transcatheter mitral valve replacement using transcatheter aortic valves in patients with failing bioprostheses, rings, or severe mitral annulus calcification?
This review highlights that while valve-in-valve TMVR is a reasonable alternative for high-risk surgical patients, evidence for valve-in-ring and valve-in-MAC remains limited.
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Supports valve-in-valve TMVR consideration in high-risk patients; leaves open the role of valve-in-ring and valve-in-MAC pending prospective data.
Ureña et al. (2021) studied this question.
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