What question did this study set out to answer?

To synthesize current scientific and clinical knowledge regarding rhinoviruses and respiratory enteroviruses, focusing on their virology, clinical burden, and disease mechanisms.

January 11, 2016SHILAP Revista de lepidopterologíaOpen Access

Rhinoviruses and Respiratory Enteroviruses: Not as Simple as ABC

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Authors

LRLéna RoystonMcGill University Health Centre CTCaroline TapparelUniversity of Geneva

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Implication

Updates RV/EV biology and clinical insights; extends literature but leaves open need for prospective validation before practice change.

Key Points

To synthesize current scientific and clinical knowledge regarding rhinoviruses and respiratory enteroviruses, focusing on their virology, clinical burden, and disease mechanisms.
Reviewed published clinical, epidemiological, and fundamental virological data on rhinoviruses (species A, B, and C) and respiratory enteroviruses (species A, B, C, and D) within the family Picornaviridae.
Assessed recent advances in molecular diagnostics that detect lower respiratory tract involvement, systemic viral spread, and emerging variants such as EV-D68.
Molecular diagnostics demonstrate that these viruses frequently infect the lower respiratory tract, contributing substantially to severe airway disease beyond simple upper respiratory common colds.
Notable lineages, including the RV-C species and epidemic EV-D68 strains, present enhanced pathogenic potential and atypical disease manifestations.
No approved antiviral treatments or preventative vaccines currently exist to manage or mitigate the substantial global disease and economic burden caused by these pathogens.

Cite This Study

Royston et al. (2016) studied this question.

synapsesocial.com/papers/69d56eb075589c71d767d50d https://doi.org/10.3390/v8010016

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Rhinoviruses and Respiratory Enteroviruses: Not as Simple as ABC

Discussion

Member takes

Implication

Key Points

Cite This Study

Rhinoviruses and Respiratory Enteroviruses: Not as Simple as ABC

Discussion

Member takes

Implication

Key Points

Cite This Study

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