Why the study?
Does increasing contact force increase lesion depth during pulsed field catheter ablation in ventricular tissue?
Does increasing contact force increase lesion depth during pulsed field catheter ablation in ventricular tissue?
Electrode-tissue contact force is required for effective lesion formation during pulsed field ablation, and increasing contact force significantly increases lesion depth.
Answers are grounded in this paper and cite their sources.
May influence ventricular PFA lesion depth; hypothesis-generating and requires clinical validation.
Acute PFA ventricular lesions show irreversible and reversible lesion boundaries by triphenyl tetrazolium chloride staining. Electrode-tissue contact is required for effective lesion formation during PFA. At the same PFA dose, lesion depth increases significantly with increasing CF.
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Nakagawa et al. (2023) studied this question.
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