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March 8, 2011Pharmacoepidemiology and Drug Safety

An automated database case definition for serious bleeding related to oral anticoagulant use

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Population

Patients with oral anticoagulant use and bleeding-related hospitalizations

Design

Other

Authors

ACAndrew CunninghamCSChristoph SteinCCCecilia P. Chung

Discussion

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Overview

High-PPV definition supports reliable bleeding ascertainment in anticoagulant database studies; leaves open external validation needs.

Structured PICO

P
Population
Patients with oral anticoagulant use and bleeding-related hospitalizations
I
Intervention
Automated database case definition for serious bleeding
O
Outcome
Positive predictive value for bleeding-related hospitalizations

An automated database case definition for serious bleeding related to oral anticoagulants demonstrates high positive predictive value (89-99%) for identifying bleeding-related hospitalizations.

Cite This Study

Cunningham et al. (2011) studied this question.

synapsesocial.com/papers/69d56ecc75589c71d767d683https://doi.org/10.1002/pds.2109
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