Why the study?
Does long-term anticoagulant therapy reduce recurrent venous thromboembolism in patients with a first episode of VTE?
Population
Patients with a first episode of venous thromboembolism (VTE)
Design
Review
Authors
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Supports risk stratification for extended anticoagulation after first VTE; leaves optimal duration open pending prospective trials.
Does long-term anticoagulant therapy reduce recurrent venous thromboembolism in patients with a first episode of VTE?
Assessing the risk-benefit ratio of long-term anticoagulation after a first VTE requires evaluating clinical risk factors, D-dimer levels, and residual venous thrombosis.
Zhu et al. (2009) studied this question.
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