April 25, 2008European Journal of Heart FailureOpen Access

Genetic Polymorphism of the Type A Human Natriuretic Peptide Receptor (NPR-A) Gene Contributes to the Interindividual Variability in the BNP System

View Full Paper

Ask AI

Bookmark

Why the study?

Does the '4-minus' haplotype of the NPR-A receptor gene affect NT-proBNP values in healthy individuals and patients with cardiovascular disorders?

Structured PICO

Does the '4-minus' haplotype of the NPR-A receptor gene affect NT-proBNP values in healthy individuals and patients with cardiovascular disorders?

Population

Healthy individuals and patients with cardiovascular disorders

Intervention

Presence of the '4-minus' haplotype of the NPR-A receptor gene

Outcome

NT-proBNP valuessurrogate

Genetic variation in the NPR-A gene contributes to baseline differences in NT-proBNP levels among healthy individuals, which may be important for interpreting this biomarker.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

NT-proBNP interpretation may require genotype consideration in healthy individuals; leaves open impact in cardiovascular disorders.

Cite This Study

Weber et al. (2008) studied this question.

synapsesocial.com/papers/69d56ee475589c71d767d778 https://doi.org/10.1016/j.ejheart.2008.03.009

View Full Paper

Ask AI

Bookmark

Genetic Polymorphism of the Type A Human Natriuretic Peptide Receptor (NPR-A) Gene Contributes to the Interindividual Variability in the BNP System

Structured PICO

Discussion

Implication

Cite This Study

Genetic Polymorphism of the Type A Human Natriuretic Peptide Receptor (NPR-A) Gene Contributes to the Interindividual Variability in the BNP System

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider