Why the study?
Does cardiac transplantation prevent death in young adults with giant-cell myocarditis?
Does cardiac transplantation prevent death in young adults with giant-cell myocarditis?
Cardiac transplantation is the treatment of choice for giant-cell myocarditis to prevent death from heart failure and ventricular arrhythmia.
Prioritizes urgent transplantation referral in giant-cell myocarditis to avert fatal outcomes; leaves open prospective trials of alternatives or timing.
Giant-cell myocarditis is a disease of relatively young, predominantly healthy adults. Patients usually die of heart failure and ventricular arrhythmia unless cardiac transplantation is performed. Despite the possibility of fatal disease recurrence, transplantation is the treatment of choice for most patients.
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Cooper et al. (1997) studied this question.
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