What question did this study set out to answer?

To report a case of idiopathic giant cell myocarditis presenting with monomorphic ventricular tachycardia and describe the diagnostic and therapeutic management.

June 19, 2019Case Reports in CardiologyOpen Access

Monomorphic Ventricular Tachycardia as a Presentation of Giant Cell Myocarditis

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Why the study?

Giant cell myocarditis is a rare, often fatal disorder with a challenging diagnosis where therapy may improve prognosis.

Population

One 54-year-old female presenting with hemodynamically significant ventricular arrhythmia

Design

Case report

Authors

MCMichael ChiuUniversity of Calgary CTCvetan TrpkovValve (United States)SRSaman RezazedehUniversity of Calgary

Discussion

Member takes

Implication

Case supports early biopsy in fulminant myocarditis with arrhythmia; leaves open optimal immunosuppression strategies pending controlled data.

Key Points

To report a case of idiopathic giant cell myocarditis presenting with monomorphic ventricular tachycardia and describe the diagnostic and therapeutic management.
Evaluated a previously healthy 54-year-old female presenting with hemodynamically significant ventricular arrhythmia and severe left ventricular dysfunction.
Conducted cardiac MRI and endomyocardial biopsy to evaluate suspected myocarditis and confirm histopathology.
Initiated combined immunosuppressive therapy alongside guideline-directed medical therapy and implanted a secondary prevention cardioverter defibrillator.
Endomyocardial biopsy confirmed idiopathic giant cell myocarditis driven by T lymphocyte-mediated myocardial inflammation.
Treatment with combined immunosuppressive therapy and an implantable cardioverter defibrillator successfully stabilized cardiac function and addressed high-risk dysrhythmia.

Structured PICO

Population

A previously healthy 54-year-old female presenting with hemodynamically significant ventricular arrhythmia and severe left ventricular dysfunction due to giant cell myocarditis.

Intervention

Combined immunosuppressive therapy, guideline-directed medical therapy, and secondary prevention implantable cardioverter defibrillator (ICD) implantation.

Giant cell myocarditis is a rare, fulminant condition that can present with ventricular arrhythmia and requires a high index of suspicion for prompt diagnosis via biopsy and treatment with immunosuppression and ICD implantation.

Cite This Study

Chiu et al. (2019) studied this question.

synapsesocial.com/papers/6a6fe383439bab0cabc2f119 https://doi.org/10.1155/2019/7276516

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Implication

Case supports early biopsy in fulminant myocarditis with arrhythmia; leaves open optimal immunosuppression strategies pending controlled data.

Monomorphic Ventricular Tachycardia as a Presentation of Giant Cell Myocarditis

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Monomorphic Ventricular Tachycardia as a Presentation of Giant Cell Myocarditis

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider