Key result
Immunosuppressant drugs resulted in a relative improvement of arrhythmia and heart failure symptoms in three patients with biopsy-proven giant cell myocarditis.
Why the study?
Do immunosuppressant drugs improve arrhythmia and heart failure symptoms in patients with giant cell myocarditis?
Case Report (n=3)
Do immunosuppressant drugs improve arrhythmia and heart failure symptoms in patients with giant cell myocarditis?
Immunosuppressive therapy may provide relative improvement in arrhythmia and heart failure symptoms in patients with giant cell myocarditis.
Hypothesis-generating for immunosuppression in giant cell myocarditis; prospective trials needed before clinical adoption.
Introduction: Although giant cell myocarditis (GCM) is a rare, potentially fatal disease but its true prevalence is likely to be underestimated. GCM can lead to progressive heart failure, fatal ventricular arrhythmia and atrio-ventricular block. Case Presentation: The present report describes three cases of biopsy-proven GCM with clinical presentation including arrhythmia and heart failure. All patients were treated with immunosuppressant drugs. Conclusions: Arrhythmia and symptoms of heart failure with immunosuppression had a relative improvement in three patients.
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Khoshavi et al. (2018) conducted a case report in Giant cell myocarditis (n=3). Immunosuppressant drugs was evaluated on Improvement in arrhythmia and symptoms of heart failure. Immunosuppressant drugs resulted in a relative improvement of arrhythmia and heart failure symptoms in three patients with biopsy-proven giant cell myocarditis.
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