Key result
A 65-year-old woman with idiopathic giant cell myocarditis died from disease complications despite ICD placement and combined immunosuppressive therapy.
Why the study?
Idiopathic giant cell myocarditis is an uncommon, frequently fatal myocarditis that primarily affects young individuals, prompting the presentation of an unusual case in an older adult alongside a review of its natural history and treatment.
Case Report (n=1)
This case highlights the importance of considering endomyocardial biopsy to diagnose rare, fatal conditions like giant cell myocarditis in patients with atypical, refractory heart failure.
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IGCM warrants biopsy consideration in refractory nonischemic HF at any age; leaves open optimal immunosuppression strategies without transplant.
González-Moret et al. (2024) conducted a case report in Idiopathic giant cell myocarditis (n=1). Implantable cardioverter-defibrillator (ICD) and combined immunosuppressive therapy was evaluated. A 65-year-old woman with idiopathic giant cell myocarditis died from disease complications despite ICD placement and combined immunosuppressive therapy.
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