Why the study?
Is blunted diurnal blood pressure variation associated with a subsequent decline in glomerular filtration rate?
Is blunted diurnal blood pressure variation associated with a subsequent decline in glomerular filtration rate?
Blunted diurnal blood pressure variation is an independent predictor of subsequent renal function deterioration.
Blunted diurnal BP variation may flag higher renal risk beyond SBP load; hypothesis-generating for whether restoring variation slows GFR decline.
Blunted diurnal blood pressure variation is associated with a subsequent deterioration in renal function that is independent of SBP load and other risk factors for renal impairment.
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Davidson et al. (2006) studied this question.
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