Coronary Artery Disease and 10-Year Outcome After Hospital Admission for Heart Failure with Preserved and with Reduced Ejection Fraction

Dan Ruşinaru; David Houpe; Catherine Szymanski; Franck Lévy; Sylvestre Maréchaux; Christophe Tribouilloy

doi:10.1002/ejhf.142

August 11, 2014European Journal of Heart Failure

Coronary Artery Disease and 10-Year Outcome After Hospital Admission for Heart Failure with Preserved and with Reduced Ejection Fraction

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Why the study?

Does the presence of coronary artery disease differentially impact 10-year outcomes in patients hospitalized for HFPEF compared to HFREF?

Key Points

Assess and compare the 10-year prognostic impact of coronary artery disease in patients hospitalized for heart failure with preserved versus reduced ejection fraction.
Tracked 10-year post-admission outcomes in patients hospitalized for heart failure.
Stratified patients by heart failure subtype—heart failure with preserved ejection fraction (HFpEF) versus reduced ejection fraction (HFrEF)—and coronary artery disease status.
The long-term prognostic impact of coronary artery disease varies significantly between patients with HFpEF and HFrEF.
Patients with comorbid HFpEF and coronary artery disease experience elevated rates of cardiovascular death, driven primarily by sudden death.

Structured PICO

Does the presence of coronary artery disease differentially impact 10-year outcomes in patients hospitalized for HFPEF compared to HFREF?

P

Population

Patients admitted to the hospital for heart failure with preserved ejection fraction (HFPEF) and heart failure with reduced ejection fraction (HFREF)

I

Intervention

Presence of coronary artery disease (CAD)

C

Comparator

Absence of CAD / HFREF with CAD

O

Outcome

10-year outcome (cardiovascular death, sudden death)hard clinical

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Implication

Coronary artery disease carries a distinct and severe prognostic impact in patients with HFpEF, placing them at particularly high risk for cardiovascular and sudden death over a 10-year period.

Abstract

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Cite This Study

Ruşinaru et al. (2014) studied this question.

synapsesocial.com/papers/69d56f7575589c71d767d8c5 https://doi.org/10.1002/ejhf.142

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Coronary Artery Disease and 10-Year Outcome After Hospital Admission for Heart Failure with Preserved and with Reduced Ejection Fraction

Key Points

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Coronary Artery Disease and 10-Year Outcome After Hospital Admission for Heart Failure with Preserved and with Reduced Ejection Fraction

Key Points

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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