Does a CVB1 vaccine prevent CVB1 infection and CVB1-induced diabetes in an experimental mouse model of type 1 diabetes?
A CVB1 vaccine provides preclinical proof of concept for protecting against virus-induced diabetes in a mouse model, supporting further research into enterovirus vaccines for human type 1 diabetes.
CVB1 vaccine can efficiently protect against both CVB1 infection and CVB1-induced diabetes. This preclinical proof of concept study provides a base for further studies aimed at developing a vaccine for use in elucidating the role of enteroviruses in human type 1 diabetes.
Stone et al. (Sat,) studied this question.