The natural history of isolated left ventricular non-compaction is highly variable, with symptomatic patients (heart failure, VT) having a worse prognosis than those with incidental discovery.
May guide follow-up intensity in IVNC by symptoms and LA size; leaves open prospective validation.
IVNC is associated with a broad spectrum of clinical and pathophysiological findings, and the overall natural history and prognosis may be better than previously thought. Adult patients with incidental or familial discovery of IVNC have an encouraging outlook, whereas those who have symptoms of heart failure, a history of sustained ventricular tachycardia or an enlarged left atrium have an unstable course and more severe prognosis.
No takes yet. Share an insight, caveat, or question.
Lofiego et al. (2006) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: