Epidemiology and treatment of depression in patients with chronic medical illness
Why the study?
Are evidence-based psychotherapies, antidepressant medications, and collaborative care effective for treating depression in patients with chronic medical illness?
Population
Patients with chronic medical illness and comorbid depression
Design
Review
Authors
Discussion
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Member takes
Implication
Supports collaborative care for comorbid depression; leaves open optimal strategies across specific chronic conditions.
Key Points
- To review the bidirectional relationship, biological mechanisms, and treatment strategies for depression co-occurring with chronic medical illness.
- Synthesized epidemiological and clinical literature addressing the biological, behavioral, and functional impacts of depression comorbid with chronic physical diseases.
- Evaluated the efficacy of pharmacological, psychotherapeutic, and primary care delivery approaches for managing comorbid depression.
- Comorbid depression exacerbates medical symptom severity, functional disability, healthcare expenditures, treatment nonadherence, and mortality through inflammatory, neuroendocrine, autonomic, and metabolic pathways.
- Evidence-based psychotherapies and antidepressant medications are efficacious interventions for reducing depressive symptom burden in medically ill populations.
- Collaborative depression care models effectively deliver evidence-based psychological and pharmacological treatments across large primary care patient cohorts.
Structured PICO
Are evidence-based psychotherapies, antidepressant medications, and collaborative care effective for treating depression in patients with chronic medical illness?
P
Population
Patients with chronic medical illness and comorbid depression
I
Intervention
Evidence-based psychotherapies, antidepressant medication, and collaborative depression care
Comorbid depression worsens the course of chronic medical disorders, but can be effectively managed with collaborative care, psychotherapy, and antidepressants.
Cite This Study
Wayne Katon (2011) studied this question.