Structural Framework for the Protein Kinase Family

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Predicted structures of the cGMP binding domains of the cGMP-dependent protein kinase: a key alanine/threonine difference in evolutionary divergence of cAMP and cGMP binding sites1989 · 125 citations
2. 2Neither arginine nor histidine can carry out the function of lysine-295 in the ATP-binding site of p60src.1986 · 157 citations
3. 3Rational scanning mutagenesis of a protein kinase identifies functional regions involved in catalysis and substrate interactions1991 · 339 citations
4. 4Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin- and antibody-stimulated glucose uptake and receptor kinase activity.1987 · 398 citations
5. 5The src protein contains multiple domains for specific attachment to membranes.1990 · 111 citations