Why the study?
What are the electrocardiographic precursors (sympathetic tone changes and cardiac pauses) leading to ventricular fibrillation in patients undergoing Holter monitoring?
What are the electrocardiographic precursors (sympathetic tone changes and cardiac pauses) leading to ventricular fibrillation in patients undergoing Holter monitoring?
Ventricular fibrillation is preceded by distinct heart rate trends depending on the etiology: progressive bradycardia and pauses in torsades de pointes, versus tachycardia and shorter coupling intervals in coronary patients.
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Distinct pre-VF heart rate trends by etiology merit vigilance on monitoring; hypothesis-generating for etiology-specific risk prediction.
Leclercq et al. (1988) studied this question.
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