Propensity-Matched Comparisons of Clinical Outcomes After Transapical or Transfemoral Transcatheter Aortic Valve Replacement

Key Points

• To compare clinical outcomes and procedural efficacy between transapical and transfemoral access routes in patients undergoing transcatheter aortic valve replacement.
• Clinical trial analysis registered under identifier NCT00530894 evaluating transcatheter aortic valve replacement.
• Propensity-matched comparative analysis applied to balance baseline clinical characteristics between transapical and transfemoral cohorts.
• Clinical outcomes were evaluated across propensity-matched cohorts to measure procedural success and post-implantation complications.
• Comparative access-route metrics highlight distinct procedural considerations between apical and femoral arterial approaches.