Key result
CMR-quantified extracellular volume expansion linked to higher short-term mortality and heart failure composite events.
Why the study?
Do ECV measures of extracellular matrix expansion quantified by CMR predict short-term mortality and composite end points?
Do ECV measures of extracellular matrix expansion quantified by CMR predict short-term mortality and composite end points?
ECV measures by CMR may be useful for predicting short-term mortality and advanced heart failure outcomes.
May support refined HF risk stratification; leaves open prospective validation of incremental value over standard markers.
ECV measures of extracellular matrix expansion may predict mortality as well as other composite end points (death/cardiac transplant/left ventricular assist device implantation).
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Wong et al. (2012) studied this question. Extracellular volume measures of extracellular matrix expansion may predict short-term mortality and composite endpoints including death, cardiac transplant, or LVAD implantation.
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