Why the study?
Cardiac ECV mapping has gained significant attention in basic research and clinical settings, particularly for its role in myocardial fibrosis and other cardiovascular diseases.
Cardiac ECV mapping using CMR is a valuable tool for assessing myocardial fibrosis and offers diagnostic and prognostic insights in various cardiovascular diseases.
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ECV mapping aids fibrosis assessment in research; leaves open standardization and routine clinical adoption pending validation.
Myocardial Extracellular volume fraction (ECV) mapping, based on cardiac magnetic resonance (CMR), is a crucial technique for assessing myocardial histological changes by evaluating extracellular matrix expansion. In recent years, cardiac ECV mapping has gained significant attention in both basic research and clinical settings, particularly for its role in myocardial fibrosis and other cardiovascular diseases. This review explores the measurement of ECV mapping, its diagnostic and prognostic value in ischemic and non-ischemic cardiovascular diseases, and emerging advancements in ECV mapping techniques.
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Hedges et al. (2025) studied this question.
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