January 1, 2012Journal of Cardiovascular Magnetic ResonanceOpen Access

Extracellular volume fraction mapping in the myocardium, part 1: evaluation of an automated method

View Full Paper

Ask AI

Bookmark

Why the study?

Does an automated motion correction and co-registration method improve the image quality of myocardial ECV maps in patients undergoing CMR?

Population

952 patients referred for cardiovascular magnetic resonance assessment of known or suspected heart disease…

Comparison

Automated method for generating pixel-wise… vs ECV maps generated without motion correction and…

Design

Cohort

Authors

PKPeter KellmanCardiac Imaging JWJoel WilsonOverlake Hospital Medical Center HXHui XueQingdao University

Discussion

Member takes

Implication

Supports feasibility of automated ECV mapping in CMR; leaves open need for prospective validation before routine adoption.

Structured PICO

Does an automated motion correction and co-registration method improve the image quality of myocardial ECV maps in patients undergoing CMR?

Population

952 patients referred for cardiovascular magnetic resonance (CMR) assessment of known or suspected heart disease, including a subset of 62 normal subjects used to define normal values.

Intervention

Automated method for generating pixel-wise myocardial extracellular volume fraction (ECV) maps incorporating respiratory motion correction and co-registration of pre- and post-contrast T1-maps.

Comparator

ECV maps generated without motion correction and co-registration.

Outcome

Image quality score of ECV maps (visually scored on a 5-point scale from 1=non-diagnostic to 5=excellent).surrogate

Fully automated motion correction and co-registration of breath-holds significantly improve the quality of ECV maps, making quantitative diffuse myocardial fibrosis assessment feasible for routine clinical workflow.

Limitations

Patient movement causing significant geometric distortion in a small number of cases
Difficulty distinguishing partial volume border pixels from true pathophysiology

Cite This Study

Kellman et al. (2012) studied this question.

synapsesocial.com/papers/6a7f83040d0db10a38907820 https://doi.org/10.1186/1532-429x-14-63

Topics

Cardiac MRI Cardiomyopathy

View Full Paper

Ask AI

Bookmark

Extracellular volume fraction mapping in the myocardium, part 1: evaluation of an automated method

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Topics

Extracellular volume fraction mapping in the myocardium, part 1: evaluation of an automated method

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Topics

Also Consider