Population
Murine models (adult mouse heart, mouse embryos days 8-16 postcoitum, and embryonic stem cells in vitro)
Comparison
Cloning and expression analysis of atrial myosin… vs Ventricular myosin regulatory light chain…
Design
Preclinical
Authors
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Offers potential markers for early chamber specification in stem cell models; leaves open clinical translation pending further validation.
The region-specific expression of MLC-2a and MLC-2v provides genetic markers for atrial and ventricular chamber specification during early cardiogenesis.
Kubalak et al. (1994) studied this question.
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