January 1, 2000Cytogenetic and Genome Research
The murine atrial myosin light chain-2 gene:a member of an evolutionarily conserved family of contractile proteins
Key result
The murine genomic sequence of the atrial myosin light chain-2 gene (Mylc2a) was identified, revealing highly conserved intron-exon boundaries and 95% amino acid homology between human and mouse.
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Discussion
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Implication
Supports murine models for Mylc2a; leaves open functional validation and clinical relevance in human atrial disease.
Key Points
Key points are not available for this paper at this time.
Cite This Study
Doevendans et al. (2000) studied this question. The murine genomic sequence of the atrial myosin light chain-2 gene (Mylc2a) was identified, revealing highly conserved intron-exon boundaries and 95% amino acid homology between human and mouse.