Population
Primary neonatal rat myocardial cells and a non-myocardial cell line (CV-1)
Design
Preclinical
Authors
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Offers no immediate clinical implications; extends molecular insights into cardiac gene expression while requiring in vivo validation.
The study identifies a 250-bp proximal regulatory sequence in the 5'-flanking region of the rat cardiac MLC-2 gene that directs cardiac-specific expression.
Henderson et al. (1989) studied this question.
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