Narrative review evaluates methodological advances and physical limitations in microcirculation assessment, highlighting strategies to improve laser Doppler flowmetry accuracy.
Laser Doppler flowmetry is a non-invasive method of measuring microcirculatory blood flow in tissue. In this review the technique is discussed in detail. The theoretical and experimental developments to improve the technique are reviewed. The limitations of the method are elaborated upon, and the research done so far to overcome these limitations is critically assessed.
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Rajan et al. (2008) studied this question.
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